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Introduction Gallstones, also known as cholelithiasis, are solid deposits that form in the gallbladder or bile ducts. They are typically made up of cholesterol or bilirubin, which is a pigment derived from the breakdown of red blood cells. Gallstones can range in size from tiny particles to larger, golf ball-sized stones. Gallstones form when there is an imbalance in the substances that make up bile, a digestive fluid produced by the liver and stored in the gallbladder. The exact cause of gallstone formation is not fully understood. Types of gall stones Gallstones can be classified into two main types: 1. Cholesterol Gallstones: These are the most common type, accounting for about 80% of gallstones. Cholesterol gallstones are made up primarily of cholesterol, which is a fatty substance. They form when there is an imbalance in the components of bile, causing cholesterol to crystallize and form solid stones. Cholesterol gallstones are usually yellow-green in color and can vary in size. 2. Pigment Gallstones: Pigment gallstones are less common and account for about 20% of gallstones. They are composed of bilirubin, a pigment that forms when red blood cells break down. Pigment gallstones can be either black or brown in color. Black pigment stones are typically associated with conditions such as liver disease or blood disorders, while brown pigment stones are often seen in individuals with conditions that affect the bile ducts, such as infections or strictures. It's important to note that some gallstones may contain a mixture of cholesterol and pigment components. The size, number, and composition of gallstones can vary among individuals. Gallstones can range from very tiny, sand-like particles to larger stones that can cause symptoms and complications. The formation of gallstones can be influenced by factors such as diet, obesity, genetics, and certain medical conditions. Treatment for gallstones may involve lifestyle modifications, medication to dissolve the stones, or surgical removal of the gallbladder (cholecystectomy) if necessary. Signs & Symptoms of gall stones Gallstones do not always cause symptoms, and some people may have gallstones without being aware of them. However, when gallstones become trapped in the bile ducts or cause inflammation in the gallbladder, they can lead to various signs and symptoms. Common signs and symptoms of gallstones include: 1. Abdominal Pain: The most characteristic symptom of gallstones is abdominal pain, often referred to as biliary colic. The pain is typically located in the upper right abdomen but can also radiate to the back or right shoulder. The pain may come and go and can be intense, lasting from minutes to several hours. 2. Nausea and Vomiting: Gallstones can cause nausea and may be accompanied by episodes of vomiting. 3. Jaundice: If a gallstone obstructs the bile ducts, it can prevent the flow of bile from the liver to the small intestine. This can result in a buildup of bilirubin in the bloodstream, leading to yellowing of the skin and eyes (jaundice). Other symptoms of jaundice may include dark urine and pale stools. 4. Bloating and Indigestion: Some individuals with gallstones may experience bloating, gas, and indigestion-like symptoms, such as belching or a feeling of fullness after meals. 5. Fever and Chills: If a gallstone causes inflammation or infection in the gallbladder (acute cholecystitis), it can lead to fever and chills. It's important to note that the severity and frequency of symptoms can vary among individuals. Some people may have occasional mild symptoms, while others may experience more frequent and intense symptoms. If you experience persistent or severe abdominal pain or other symptoms suggestive of gallstones, it is advisable to seek medical evaluation for proper diagnosis and management.